Objective: To investigate the etiological mechanisms, treatment and oral manifestations of inflammatory bowel disease (IBD) in relation to recurrent aphthous ulcer (RAU). Materials and Methods: By summarizing and reviewing the research in the literature on the etiological mechanisms and treatment of RAU and IBD in the past decade in China and abroad. By summarizing and reviewing the research in the literature on the etiological mechanisms and treatment of RAU and IBD in the past decade in China and abroad. To explore the interaction between oral and intestinal lesions. Results: Some specific bacteria in the oral cavity may translocate and colonize the intestine, affecting the microecological balance of the gut and interfering with the disease process of IBD. Also, in patients with IBD, their oral salivary microbiome is altered and may show extraintestinal manifestations such as oral mucosal lesions. The occurrence of RAU may aggravate the dysbiosis and immune abnormalities of the intestinal mucosal flora that will be indirectly caused by patients with IBD, as well as malnutrition. Conclusion: Patients with IBD and RAU can affect the microecology of the oral-intestinal axis. patients with IBD are at increased risk of oral mucosal disease and oral symptoms and are associated with the activity of IBD. Due to the complex pathogenic interactions between RAU and IBD. It is recommended that dentists and gastroenterologists should be aware of the bidirectional association between the two diseases for early recognition and multidisciplinary medical management.
| Published in | Clinical Medicine Research (Volume 11, Issue 6) |
| DOI | 10.11648/j.cmr.20221106.14 |
| Page(s) | 172-177 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Recurrent Aphthous Ulcers, Inflammatory Bowel Disease, Dysbiosis, Immune Dysregulation
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APA Style
Xiang Guo, Jing-Yi Zhong, Sunchuri Diwas, Meng-Fei Zhou, Long Lian, et al. (2022). Bidirectional Study of Oral Recurrent Aphthous Ulcers and Inflammatory Bowel Disease. Clinical Medicine Research, 11(6), 172-177. https://doi.org/10.11648/j.cmr.20221106.14
ACS Style
Xiang Guo; Jing-Yi Zhong; Sunchuri Diwas; Meng-Fei Zhou; Long Lian, et al. Bidirectional Study of Oral Recurrent Aphthous Ulcers and Inflammatory Bowel Disease. Clin. Med. Res. 2022, 11(6), 172-177. doi: 10.11648/j.cmr.20221106.14
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Download@article{10.11648/j.cmr.20221106.14,
author = {Xiang Guo and Jing-Yi Zhong and Sunchuri Diwas and Meng-Fei Zhou and Long Lian and Si-Yu Tao and Zhu-Ling Guo},
title = {Bidirectional Study of Oral Recurrent Aphthous Ulcers and Inflammatory Bowel Disease},
journal = {Clinical Medicine Research},
volume = {11},
number = {6},
pages = {172-177},
doi = {10.11648/j.cmr.20221106.14},
url = {https://doi.org/10.11648/j.cmr.20221106.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20221106.14},
abstract = {Objective: To investigate the etiological mechanisms, treatment and oral manifestations of inflammatory bowel disease (IBD) in relation to recurrent aphthous ulcer (RAU). Materials and Methods: By summarizing and reviewing the research in the literature on the etiological mechanisms and treatment of RAU and IBD in the past decade in China and abroad. By summarizing and reviewing the research in the literature on the etiological mechanisms and treatment of RAU and IBD in the past decade in China and abroad. To explore the interaction between oral and intestinal lesions. Results: Some specific bacteria in the oral cavity may translocate and colonize the intestine, affecting the microecological balance of the gut and interfering with the disease process of IBD. Also, in patients with IBD, their oral salivary microbiome is altered and may show extraintestinal manifestations such as oral mucosal lesions. The occurrence of RAU may aggravate the dysbiosis and immune abnormalities of the intestinal mucosal flora that will be indirectly caused by patients with IBD, as well as malnutrition. Conclusion: Patients with IBD and RAU can affect the microecology of the oral-intestinal axis. patients with IBD are at increased risk of oral mucosal disease and oral symptoms and are associated with the activity of IBD. Due to the complex pathogenic interactions between RAU and IBD. It is recommended that dentists and gastroenterologists should be aware of the bidirectional association between the two diseases for early recognition and multidisciplinary medical management.},
year = {2022}
}
TY - JOUR T1 - Bidirectional Study of Oral Recurrent Aphthous Ulcers and Inflammatory Bowel Disease AU - Xiang Guo AU - Jing-Yi Zhong AU - Sunchuri Diwas AU - Meng-Fei Zhou AU - Long Lian AU - Si-Yu Tao AU - Zhu-Ling Guo Y1 - 2022/12/15 PY - 2022 N1 - https://doi.org/10.11648/j.cmr.20221106.14 DO - 10.11648/j.cmr.20221106.14 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 172 EP - 177 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20221106.14 AB - Objective: To investigate the etiological mechanisms, treatment and oral manifestations of inflammatory bowel disease (IBD) in relation to recurrent aphthous ulcer (RAU). Materials and Methods: By summarizing and reviewing the research in the literature on the etiological mechanisms and treatment of RAU and IBD in the past decade in China and abroad. By summarizing and reviewing the research in the literature on the etiological mechanisms and treatment of RAU and IBD in the past decade in China and abroad. To explore the interaction between oral and intestinal lesions. Results: Some specific bacteria in the oral cavity may translocate and colonize the intestine, affecting the microecological balance of the gut and interfering with the disease process of IBD. Also, in patients with IBD, their oral salivary microbiome is altered and may show extraintestinal manifestations such as oral mucosal lesions. The occurrence of RAU may aggravate the dysbiosis and immune abnormalities of the intestinal mucosal flora that will be indirectly caused by patients with IBD, as well as malnutrition. Conclusion: Patients with IBD and RAU can affect the microecology of the oral-intestinal axis. patients with IBD are at increased risk of oral mucosal disease and oral symptoms and are associated with the activity of IBD. Due to the complex pathogenic interactions between RAU and IBD. It is recommended that dentists and gastroenterologists should be aware of the bidirectional association between the two diseases for early recognition and multidisciplinary medical management. VL - 11 IS - 6 ER -
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