Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature

Maria Sofia Cotelli; Filippo Manelli; Marinella Turla

doi:doi:10.11648/j.cmr.20190804.13

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Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature

Maria Sofia Cotelli, Filippo Manelli, Marinella Turla

Published in Clinical Medicine Research (Volume 8, Issue 4)

Received: 14 August 2019 Accepted: 26 August 2019 Published: 12 September 2019

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Abstract

In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts-novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. The interplay between the microbial and host factors that dictate whether and how the immune response shifts towards autoreactivity is still unclear, and nothing is known about the genetic and environmental factors that affect an individual's susceptibility to the disease. Facial Diplegia with Paresthesias is a rare localized variant of GBS in which patient presents with simultaneous facial diplegia, distal limb paresthesias and minimal or no motor weakness. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care. A common misconception is that the Guillain–Barré syndrome has a good prognosis-but up to 20% of patients remain severely disabled and approximately 5% die, despite immunotherapy. We report the case of a woman with acute facial dyplegia and rhabdomyolisis improved after immunoglobulin treatment.

Published in	Clinical Medicine Research (Volume 8, Issue 4) This article belongs to the Special Issue Neurology Emergency
DOI	10.11648/j.cmr.20190804.13
Page(s)	85-92
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Facial Dyplegia, Hyperckemia, Guillain Barrè Syndrome

References

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APA Style

Maria Sofia Cotelli, Filippo Manelli, Marinella Turla. (2019). Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature. Clinical Medicine Research, 8(4), 85-92. https://doi.org/10.11648/j.cmr.20190804.13

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ACS Style

Maria Sofia Cotelli; Filippo Manelli; Marinella Turla. Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature. Clin. Med. Res. 2019, 8(4), 85-92. doi: 10.11648/j.cmr.20190804.13

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AMA Style

Maria Sofia Cotelli, Filippo Manelli, Marinella Turla. Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature. Clin Med Res. 2019;8(4):85-92. doi: 10.11648/j.cmr.20190804.13

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@article{10.11648/j.cmr.20190804.13,
  author = {Maria Sofia Cotelli and Filippo Manelli and Marinella Turla},
  title = {Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature},
  journal = {Clinical Medicine Research},
  volume = {8},
  number = {4},
  pages = {85-92},
  doi = {10.11648/j.cmr.20190804.13},
  url = {https://doi.org/10.11648/j.cmr.20190804.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20190804.13},
  abstract = {In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts-novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. The interplay between the microbial and host factors that dictate whether and how the immune response shifts towards autoreactivity is still unclear, and nothing is known about the genetic and environmental factors that affect an individual's susceptibility to the disease. Facial Diplegia with Paresthesias is a rare localized variant of GBS in which patient presents with simultaneous facial diplegia, distal limb paresthesias and minimal or no motor weakness. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care. A common misconception is that the Guillain–Barré syndrome has a good prognosis-but up to 20% of patients remain severely disabled and approximately 5% die, despite immunotherapy. We report the case of a woman with acute facial dyplegia and rhabdomyolisis improved after immunoglobulin treatment.},
 year = {2019}
}

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TY  - JOUR
T1  - Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature
AU  - Maria Sofia Cotelli
AU  - Filippo Manelli
AU  - Marinella Turla
Y1  - 2019/09/12
PY  - 2019
N1  - https://doi.org/10.11648/j.cmr.20190804.13
DO  - 10.11648/j.cmr.20190804.13
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 85
EP  - 92
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20190804.13
AB  - In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts-novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. The interplay between the microbial and host factors that dictate whether and how the immune response shifts towards autoreactivity is still unclear, and nothing is known about the genetic and environmental factors that affect an individual's susceptibility to the disease. Facial Diplegia with Paresthesias is a rare localized variant of GBS in which patient presents with simultaneous facial diplegia, distal limb paresthesias and minimal or no motor weakness. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care. A common misconception is that the Guillain–Barré syndrome has a good prognosis-but up to 20% of patients remain severely disabled and approximately 5% die, despite immunotherapy. We report the case of a woman with acute facial dyplegia and rhabdomyolisis improved after immunoglobulin treatment.
VL  - 8
IS  - 4
ER  -

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Author Information

Maria Sofia Cotelli

Neurology Unit, Azienda Socio Sanitaria Territoriale Valcamonica-Esine, Brescia, Italy
Filippo Manelli

Emergency Unit, Azienda Socio Sanitaria Territoriale Valcamonica-Esine, Brescia, Italy
Marinella Turla

Neurology Unit, Azienda Socio Sanitaria Territoriale Valcamonica-Esine, Brescia, Italy

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APA Style

Maria Sofia Cotelli, Filippo Manelli, Marinella Turla. (2019). Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature. Clinical Medicine Research, 8(4), 85-92. https://doi.org/10.11648/j.cmr.20190804.13

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ACS Style

Maria Sofia Cotelli; Filippo Manelli; Marinella Turla. Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature. Clin. Med. Res. 2019, 8(4), 85-92. doi: 10.11648/j.cmr.20190804.13

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AMA Style

Maria Sofia Cotelli, Filippo Manelli, Marinella Turla. Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature. Clin Med Res. 2019;8(4):85-92. doi: 10.11648/j.cmr.20190804.13

Copy | Download

@article{10.11648/j.cmr.20190804.13,
  author = {Maria Sofia Cotelli and Filippo Manelli and Marinella Turla},
  title = {Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature},
  journal = {Clinical Medicine Research},
  volume = {8},
  number = {4},
  pages = {85-92},
  doi = {10.11648/j.cmr.20190804.13},
  url = {https://doi.org/10.11648/j.cmr.20190804.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20190804.13},
  abstract = {In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts-novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. The interplay between the microbial and host factors that dictate whether and how the immune response shifts towards autoreactivity is still unclear, and nothing is known about the genetic and environmental factors that affect an individual's susceptibility to the disease. Facial Diplegia with Paresthesias is a rare localized variant of GBS in which patient presents with simultaneous facial diplegia, distal limb paresthesias and minimal or no motor weakness. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care. A common misconception is that the Guillain–Barré syndrome has a good prognosis-but up to 20% of patients remain severely disabled and approximately 5% die, despite immunotherapy. We report the case of a woman with acute facial dyplegia and rhabdomyolisis improved after immunoglobulin treatment.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Acute Facial Dyplegia and Rhabdomyolisis: Case Report and Review of Literature
AU  - Maria Sofia Cotelli
AU  - Filippo Manelli
AU  - Marinella Turla
Y1  - 2019/09/12
PY  - 2019
N1  - https://doi.org/10.11648/j.cmr.20190804.13
DO  - 10.11648/j.cmr.20190804.13
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 85
EP  - 92
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20190804.13
AB  - In 1916, Guillain, Barré and Strohl reported on two cases of acute flaccid paralysis with high cerebrospinal fluid protein levels and normal cell counts-novel findings that identified the disease we now know as Guillain–Barré syndrome (GBS). 100 years on, we have made great progress with the clinical and pathological characterization of GBS. GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. The interplay between the microbial and host factors that dictate whether and how the immune response shifts towards autoreactivity is still unclear, and nothing is known about the genetic and environmental factors that affect an individual's susceptibility to the disease. Facial Diplegia with Paresthesias is a rare localized variant of GBS in which patient presents with simultaneous facial diplegia, distal limb paresthesias and minimal or no motor weakness. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care. A common misconception is that the Guillain–Barré syndrome has a good prognosis-but up to 20% of patients remain severely disabled and approximately 5% die, despite immunotherapy. We report the case of a woman with acute facial dyplegia and rhabdomyolisis improved after immunoglobulin treatment.
VL  - 8
IS  - 4
ER  -

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