Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients

Jia Fu; Haimin Xiao; Xianyan Zhou; Xin Dang

doi:doi:10.11648/j.cmr.20251406.11

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Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients

Jia Fu

, Haimin Xiao^*

, Xianyan Zhou

, Xin Dang

Published in Clinical Medicine Research (Volume 14, Issue 6)

Received: 29 October 2025 Accepted: 13 November 2025 Published: 28 November 2025

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Abstract

Objective To evaluate the application effect of medication reconciliation implemented by multidisciplinary team for elderly patients with chemotherapy. Methods 104 patients who underwent chemotherapy in the general surgery department of our hospital from December 2022 to December 2023 were selected. Medication reconciliation services were developed and provided according to a multidisciplinary team collaboration model, and the general situation of potentially inappropriate medication use was investigated and statistically analyzed. The incidence of adverse drug reaction(ADR)/adverse drug event(ADE) and patient satisfaction with medication reconciliation services in elderly chemotherapy patients were evaluated before and after the intervention. Results Among the 104 elderly patients with chemotherapy, the average types of long-term drugs before admission were (5.81±2.07), 62 patients (59.62%) brought drugs, 22 patients (21.15%) used traditional Chinese medicine. According to the analysis of possible drug use risk factors in the patients, 42 patients (40.38%) of the 104 patients had 86 potentially inappropriate drugs, involving 54 drugs in 8 categories. The top 3 drugs were cardiovascular system drugs, digestive system drugs and endocrine system drugs. After the intervention, pharmacists put forward 26 drug suggestions, and doctors accepted 22 of them (84.62%). After the intervention, the incidence of ADR/ADE was lower (P<0.05), and the patient satisfaction was higher (P<0.05). Conclusion Elderly patients have many diseases, many drug risk factors and multiple drugs, so we should pay more attention to medication reconciliation. The implementation of the nurse-pharmacist-physician coordinated medication reconciliation intervention program can find the hidden dangers of drug use in time, avoid the deviation of drug therapy, and improve the drug literacy of patients. This program is an effective way of medication management for elderly patients.

Published in	Clinical Medicine Research (Volume 14, Issue 6)
DOI	10.11648/j.cmr.20251406.11
Page(s)	210-216
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Multidisciplinary Team, Medication Reconciliation, Elderly Patients, Chemotherapy, Medication Safety

References

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[2]	Daliri S, Bouhnouf M, van de Meerendonk HWPC, et al. Longitudinal medication reconciliation at hospital admission, discharge and post-discharge. Res Social Adm Pharm. 2021; 17(4): 677-684. https://doi.org/10.1016/j.sapharm.2020.05.022
[3]	Mekonnen AB, McLachlan AJ, Brien JA. Pharmacy-led medication reconciliation programmes at hospital transitions: a systematic review and meta-analysis. J Clin Pharm Ther. 2016; 41(2): 128-144. https://doi.org/10.1111/jcpt.12364
[4]	Magallón Martínez A, Pinilla Rello A, Casajús Lagranja P, et al. Pharmaceutical care for the patients admitted to a multidisciplinary complex chronic patient unit. Farm Hosp. 2023; 47(3): 106-112. https://doi.org/10.1016/j.farma.2023.01.004
[5]	Pfister B, Jonsson J, Gustafsson M. Drug-related problems and medication reviews among old people with dementia. BMC Pharmacol Toxicol. 2017; 18(1): 52. https://doi.org/10.1186/s40360-017-0157-2
[6]	Al-Hashar A, Al-Zakwani I, Eriksson T, et al. Impact of medication reconciliation and review and counselling, on adverse drug events and healthcare resource use. Int J Clin Pharm. 2018; 40(5): 1154-1164. https://doi.org/10.1007/s11096-018-0650-8
[7]	By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019; 67(4): 674-694. https://doi.org/10.1111/jgs.15767
[8]	Beuscart JB, Pelayo S, Robert L, et al. Medication review and reconciliation in older adults. Eur Geriatr Med. 2021; 12(3): 499-507. https://doi.org/10.1007/s41999-021-00449-9
[9]	Danwei W, Shuang H, Nannan X, et al. The Role of Clinical Pharmacist-Led Chronic Disease Management in Improving the Understanding of Medication in Elderly Patients with Hypertension.China Pharm. 2018; 29(23): 3251-3254. https://doi.org/10.15887/j.cnki.13-1389/r.2022.32.003
[10]	Xuhong Y, Yang L, Guanghui W, et al. Research on Medication Reconciliation and Pharmaceutical Services for Elderly Patients. Chi J of Clin Pharm. 2020; 36(2): 203-205. https://doi.org/10.13699/j.cnki.1001-6821.2020.02.028
[11]	Beuscart JB, Pelayo S, Robert L, et al. Medication review and reconciliation in older adults. Eur Geriatr Med. 2021; 12(3): 499-507. https://doi.org/10.1007/s41999-021-00449-9
[12]	Fangying S, Ying X, Xiaohong Y. Clinical Pharmacists' Practice of Medication Reconciliation for Patients with Chronic Kidney Disease. China Pharm. 2020; 31(19): 2410-2414. https://doi.org/10.6039/j.issn.1001-0408.2020.19.19

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APA Style

Fu, J., Xiao, H., Zhou, X., Dang, X. (2025). Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients. Clinical Medicine Research, 14(6), 210-216. https://doi.org/10.11648/j.cmr.20251406.11

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ACS Style

Fu, J.; Xiao, H.; Zhou, X.; Dang, X. Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients. Clin. Med. Res. 2025, 14(6), 210-216. doi: 10.11648/j.cmr.20251406.11

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AMA Style

Fu J, Xiao H, Zhou X, Dang X. Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients. Clin Med Res. 2025;14(6):210-216. doi: 10.11648/j.cmr.20251406.11

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@article{10.11648/j.cmr.20251406.11,
  author = {Jia Fu and Haimin Xiao and Xianyan Zhou and Xin Dang},
  title = {Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients
},
  journal = {Clinical Medicine Research},
  volume = {14},
  number = {6},
  pages = {210-216},
  doi = {10.11648/j.cmr.20251406.11},
  url = {https://doi.org/10.11648/j.cmr.20251406.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20251406.11},
  abstract = {Objective To evaluate the application effect of medication reconciliation implemented by multidisciplinary team for elderly patients with chemotherapy. Methods 104 patients who underwent chemotherapy in the general surgery department of our hospital from December 2022 to December 2023 were selected. Medication reconciliation services were developed and provided according to a multidisciplinary team collaboration model, and the general situation of potentially inappropriate medication use was investigated and statistically analyzed. The incidence of adverse drug reaction(ADR)/adverse drug event(ADE) and patient satisfaction with medication reconciliation services in elderly chemotherapy patients were evaluated before and after the intervention. Results Among the 104 elderly patients with chemotherapy, the average types of long-term drugs before admission were (5.81±2.07), 62 patients (59.62%) brought drugs, 22 patients (21.15%) used traditional Chinese medicine. According to the analysis of possible drug use risk factors in the patients, 42 patients (40.38%) of the 104 patients had 86 potentially inappropriate drugs, involving 54 drugs in 8 categories. The top 3 drugs were cardiovascular system drugs, digestive system drugs and endocrine system drugs. After the intervention, pharmacists put forward 26 drug suggestions, and doctors accepted 22 of them (84.62%). After the intervention, the incidence of ADR/ADE was lower (P<0.05), and the patient satisfaction was higher (P<0.05). Conclusion Elderly patients have many diseases, many drug risk factors and multiple drugs, so we should pay more attention to medication reconciliation. The implementation of the nurse-pharmacist-physician coordinated medication reconciliation intervention program can find the hidden dangers of drug use in time, avoid the deviation of drug therapy, and improve the drug literacy of patients. This program is an effective way of medication management for elderly patients.},
 year = {2025}
}

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TY  - JOUR
T1  - Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients

AU  - Jia Fu
AU  - Haimin Xiao
AU  - Xianyan Zhou
AU  - Xin Dang
Y1  - 2025/11/28
PY  - 2025
N1  - https://doi.org/10.11648/j.cmr.20251406.11
DO  - 10.11648/j.cmr.20251406.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 210
EP  - 216
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20251406.11
AB  - Objective To evaluate the application effect of medication reconciliation implemented by multidisciplinary team for elderly patients with chemotherapy. Methods 104 patients who underwent chemotherapy in the general surgery department of our hospital from December 2022 to December 2023 were selected. Medication reconciliation services were developed and provided according to a multidisciplinary team collaboration model, and the general situation of potentially inappropriate medication use was investigated and statistically analyzed. The incidence of adverse drug reaction(ADR)/adverse drug event(ADE) and patient satisfaction with medication reconciliation services in elderly chemotherapy patients were evaluated before and after the intervention. Results Among the 104 elderly patients with chemotherapy, the average types of long-term drugs before admission were (5.81±2.07), 62 patients (59.62%) brought drugs, 22 patients (21.15%) used traditional Chinese medicine. According to the analysis of possible drug use risk factors in the patients, 42 patients (40.38%) of the 104 patients had 86 potentially inappropriate drugs, involving 54 drugs in 8 categories. The top 3 drugs were cardiovascular system drugs, digestive system drugs and endocrine system drugs. After the intervention, pharmacists put forward 26 drug suggestions, and doctors accepted 22 of them (84.62%). After the intervention, the incidence of ADR/ADE was lower (P<0.05), and the patient satisfaction was higher (P<0.05). Conclusion Elderly patients have many diseases, many drug risk factors and multiple drugs, so we should pay more attention to medication reconciliation. The implementation of the nurse-pharmacist-physician coordinated medication reconciliation intervention program can find the hidden dangers of drug use in time, avoid the deviation of drug therapy, and improve the drug literacy of patients. This program is an effective way of medication management for elderly patients.
VL  - 14
IS  - 6
ER  -

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Author Information

Jia Fu

General Surgery Department I, Shaanxi Provincial People's Hospital, Xi'an, China

Contact Email

http://orcid.org/0000-0003-1554-2219
Haimin Xiao

General Surgery Department I, Shaanxi Provincial People's Hospital, Xi'an, China

Contact Email

http://orcid.org/0009-0004-9404-6671
Xianyan Zhou

General Surgery Department I, Shaanxi Provincial People's Hospital, Xi'an, China

http://orcid.org/0009-0005-5895-6018
Xin Dang

General Surgery Department I, Shaanxi Provincial People's Hospital, Xi'an, China

http://orcid.org/0009-0006-6921-4180

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APA Style

Fu, J., Xiao, H., Zhou, X., Dang, X. (2025). Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients. Clinical Medicine Research, 14(6), 210-216. https://doi.org/10.11648/j.cmr.20251406.11

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ACS Style

Fu, J.; Xiao, H.; Zhou, X.; Dang, X. Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients. Clin. Med. Res. 2025, 14(6), 210-216. doi: 10.11648/j.cmr.20251406.11

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AMA Style

Fu J, Xiao H, Zhou X, Dang X. Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients. Clin Med Res. 2025;14(6):210-216. doi: 10.11648/j.cmr.20251406.11

Copy | Download

@article{10.11648/j.cmr.20251406.11,
  author = {Jia Fu and Haimin Xiao and Xianyan Zhou and Xin Dang},
  title = {Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients
},
  journal = {Clinical Medicine Research},
  volume = {14},
  number = {6},
  pages = {210-216},
  doi = {10.11648/j.cmr.20251406.11},
  url = {https://doi.org/10.11648/j.cmr.20251406.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20251406.11},
  abstract = {Objective To evaluate the application effect of medication reconciliation implemented by multidisciplinary team for elderly patients with chemotherapy. Methods 104 patients who underwent chemotherapy in the general surgery department of our hospital from December 2022 to December 2023 were selected. Medication reconciliation services were developed and provided according to a multidisciplinary team collaboration model, and the general situation of potentially inappropriate medication use was investigated and statistically analyzed. The incidence of adverse drug reaction(ADR)/adverse drug event(ADE) and patient satisfaction with medication reconciliation services in elderly chemotherapy patients were evaluated before and after the intervention. Results Among the 104 elderly patients with chemotherapy, the average types of long-term drugs before admission were (5.81±2.07), 62 patients (59.62%) brought drugs, 22 patients (21.15%) used traditional Chinese medicine. According to the analysis of possible drug use risk factors in the patients, 42 patients (40.38%) of the 104 patients had 86 potentially inappropriate drugs, involving 54 drugs in 8 categories. The top 3 drugs were cardiovascular system drugs, digestive system drugs and endocrine system drugs. After the intervention, pharmacists put forward 26 drug suggestions, and doctors accepted 22 of them (84.62%). After the intervention, the incidence of ADR/ADE was lower (P<0.05), and the patient satisfaction was higher (P<0.05). Conclusion Elderly patients have many diseases, many drug risk factors and multiple drugs, so we should pay more attention to medication reconciliation. The implementation of the nurse-pharmacist-physician coordinated medication reconciliation intervention program can find the hidden dangers of drug use in time, avoid the deviation of drug therapy, and improve the drug literacy of patients. This program is an effective way of medication management for elderly patients.},
 year = {2025}
}

Copy | Download

TY  - JOUR
T1  - Evaluation of Multidisciplinary Medication Reconciliation in Elderly Chemotherapy Patients

AU  - Jia Fu
AU  - Haimin Xiao
AU  - Xianyan Zhou
AU  - Xin Dang
Y1  - 2025/11/28
PY  - 2025
N1  - https://doi.org/10.11648/j.cmr.20251406.11
DO  - 10.11648/j.cmr.20251406.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 210
EP  - 216
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20251406.11
AB  - Objective To evaluate the application effect of medication reconciliation implemented by multidisciplinary team for elderly patients with chemotherapy. Methods 104 patients who underwent chemotherapy in the general surgery department of our hospital from December 2022 to December 2023 were selected. Medication reconciliation services were developed and provided according to a multidisciplinary team collaboration model, and the general situation of potentially inappropriate medication use was investigated and statistically analyzed. The incidence of adverse drug reaction(ADR)/adverse drug event(ADE) and patient satisfaction with medication reconciliation services in elderly chemotherapy patients were evaluated before and after the intervention. Results Among the 104 elderly patients with chemotherapy, the average types of long-term drugs before admission were (5.81±2.07), 62 patients (59.62%) brought drugs, 22 patients (21.15%) used traditional Chinese medicine. According to the analysis of possible drug use risk factors in the patients, 42 patients (40.38%) of the 104 patients had 86 potentially inappropriate drugs, involving 54 drugs in 8 categories. The top 3 drugs were cardiovascular system drugs, digestive system drugs and endocrine system drugs. After the intervention, pharmacists put forward 26 drug suggestions, and doctors accepted 22 of them (84.62%). After the intervention, the incidence of ADR/ADE was lower (P<0.05), and the patient satisfaction was higher (P<0.05). Conclusion Elderly patients have many diseases, many drug risk factors and multiple drugs, so we should pay more attention to medication reconciliation. The implementation of the nurse-pharmacist-physician coordinated medication reconciliation intervention program can find the hidden dangers of drug use in time, avoid the deviation of drug therapy, and improve the drug literacy of patients. This program is an effective way of medication management for elderly patients.
VL  - 14
IS  - 6
ER  -

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