Haematological Profiles of Patients with Extra-pulmonary Tuberculosis

Silas Anayochukwu Ufelle; Kenechukwu Chibuike Onyekwelu; Peter Uwadiegwu Achukwu; Augustine Chidi Ndubisi; Richard Chukwunonye Ezeh; Lorreta Nwakaego Nwokolo

doi:doi:10.11648/j.cmr.20200901.14

Haematological Profiles of Patients with Extra-pulmonary Tuberculosis

Silas Anayochukwu Ufelle, Kenechukwu Chibuike Onyekwelu, Peter Uwadiegwu Achukwu, Augustine Chidi Ndubisi, Richard Chukwunonye Ezeh, Lorreta Nwakaego Nwokolo

Published in Clinical Medicine Research (Volume 9, Issue 1)

Received: 11 August 2019 Accepted: 23 October 2019 Published: 18 February 2020

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Abstract

Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. We aimed to evaluate the complete blood count (CBC) and erythrocyte sedimentation rate (ESR) of confirmed extra-pulmonary tuberculosis (EPTB) patients attending clinic at the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu. A total of 90 confirmed extra-pulmonary tuberculosis patients consisting of male (n = 38) and female (n = 52), aged 15 to 60 years attending clinic participated in this study. CBC and ESR were analysed using Haematological Auto Analyzer and Westergren method respectively. Haemoglobin and haematocrit values across the three age groups (15-30, 31-45, 46-60 years) were significantly lower (p < 0.05) than the control value in both male and female extra-pulmonary tuberculosis patients. Erythrocyte sedimentation rate, white blood count, platelet and neutrophil values across the three were significantly higher (p < 0.05) than the control values in both male and female extra-pulmonary tuberculosis patients. Extra-pulmonary tuberculosis was observed more in females than the males and was relatively higher in older patients (above 46 years) than younger patients (below 46 years). This study was able to show that different haematological parameters such as haemoglobin, haematocrit, Erythrocyte sedimentation rate, white blood count, platelet and neutrophil could serve as hallmark and help in early diagnosis of extra-pulmonary tuberculosis.

Published in	Clinical Medicine Research (Volume 9, Issue 1)
DOI	10.11648/j.cmr.20200901.14
Page(s)	20-24
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Extra-pulmonary Tuberculosis, Comzplete Blood Count, Erythrocyte Sedimentation Rate

References

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[9]	Westergreen A (1957) Diagnostic tests: the erythrocyte sedimentation rate range and limitation of the technique: Triangle 3 (1); 20–5.
[10]	Sauders E (2007) Robbins Basic Pathology 8th Edition Cambridge Press, London. Pages 516–520.
[11]	Shafee M, Abbas F, Ashraf M, Mengal MA, Kakar N, et al. (2014) Hematological profile and risk factors associated with pulmonary tuberculosis patients in Quetta, Pakistan. Pak J Med Sci; 30 (1): 36-40.
[12]	Ayaz S, Tahira N, Khan S, Khan SN, Rubab L, et al. (2012) Pulmonary Tuberculosis: Still Prevalent in Human in Peshawar, Khyber Pakhtunkhwa. Pak J Life Soc Sci.; 10 (1): 39-41.
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[17]	Al-Hajoj S, Shoukri M, Memish Z, AlHakeem R, AlRabiah F, et al. (2015) Exploring the Sociodemographic and Clinical Features of Extrapulmonary Tuberculosis in Saudi Arabia. PLoS ONE 10 (2): e0101667. doi: 10.1371/journal.pone.017
[18]	Amin S, Khattak MI, Shabbier G, Wazir MN (2011) Frequency of Pulmonary tuberculosis in Patients With diabetes Mellitus. Gomal J Med Sci 9 (2): 163–165.
[19]	Ullah H, Iqbal Z, Ullah Z, Mahboob A, Rehman M (2009) Frequency of pulmonary tuberculosis in patients presenting with diabetes. Pak J Chest Med 15 (4): 1–7.
[20]	Means RT (2003). Recent developments in the anemia of chronic disease. Current Hematology l Rep., 2: 116-121.
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APA Style

Silas Anayochukwu Ufelle, Kenechukwu Chibuike Onyekwelu, Peter Uwadiegwu Achukwu, Augustine Chidi Ndubisi, Richard Chukwunonye Ezeh, et al. (2020). Haematological Profiles of Patients with Extra-pulmonary Tuberculosis. Clinical Medicine Research, 9(1), 20-24. https://doi.org/10.11648/j.cmr.20200901.14

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ACS Style

Silas Anayochukwu Ufelle; Kenechukwu Chibuike Onyekwelu; Peter Uwadiegwu Achukwu; Augustine Chidi Ndubisi; Richard Chukwunonye Ezeh, et al. Haematological Profiles of Patients with Extra-pulmonary Tuberculosis. Clin. Med. Res. 2020, 9(1), 20-24. doi: 10.11648/j.cmr.20200901.14

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AMA Style

Silas Anayochukwu Ufelle, Kenechukwu Chibuike Onyekwelu, Peter Uwadiegwu Achukwu, Augustine Chidi Ndubisi, Richard Chukwunonye Ezeh, et al. Haematological Profiles of Patients with Extra-pulmonary Tuberculosis. Clin Med Res. 2020;9(1):20-24. doi: 10.11648/j.cmr.20200901.14

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@article{10.11648/j.cmr.20200901.14,
  author = {Silas Anayochukwu Ufelle and Kenechukwu Chibuike Onyekwelu and Peter Uwadiegwu Achukwu and Augustine Chidi Ndubisi and Richard Chukwunonye Ezeh and Lorreta Nwakaego Nwokolo},
  title = {Haematological Profiles of Patients with Extra-pulmonary Tuberculosis},
  journal = {Clinical Medicine Research},
  volume = {9},
  number = {1},
  pages = {20-24},
  doi = {10.11648/j.cmr.20200901.14},
  url = {https://doi.org/10.11648/j.cmr.20200901.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20200901.14},
  abstract = {Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. We aimed to evaluate the complete blood count (CBC) and erythrocyte sedimentation rate (ESR) of confirmed extra-pulmonary tuberculosis (EPTB) patients attending clinic at the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu. A total of 90 confirmed extra-pulmonary tuberculosis patients consisting of male (n = 38) and female (n = 52), aged 15 to 60 years attending clinic participated in this study. CBC and ESR were analysed using Haematological Auto Analyzer and Westergren method respectively. Haemoglobin and haematocrit values across the three age groups (15-30, 31-45, 46-60 years) were significantly lower (p < 0.05) than the control value in both male and female extra-pulmonary tuberculosis patients. Erythrocyte sedimentation rate, white blood count, platelet and neutrophil values across the three were significantly higher (p < 0.05) than the control values in both male and female extra-pulmonary tuberculosis patients. Extra-pulmonary tuberculosis was observed more in females than the males and was relatively higher in older patients (above 46 years) than younger patients (below 46 years). This study was able to show that different haematological parameters such as haemoglobin, haematocrit, Erythrocyte sedimentation rate, white blood count, platelet and neutrophil could serve as hallmark and help in early diagnosis of extra-pulmonary tuberculosis.},
 year = {2020}
}

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TY  - JOUR
T1  - Haematological Profiles of Patients with Extra-pulmonary Tuberculosis
AU  - Silas Anayochukwu Ufelle
AU  - Kenechukwu Chibuike Onyekwelu
AU  - Peter Uwadiegwu Achukwu
AU  - Augustine Chidi Ndubisi
AU  - Richard Chukwunonye Ezeh
AU  - Lorreta Nwakaego Nwokolo
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PY  - 2020
N1  - https://doi.org/10.11648/j.cmr.20200901.14
DO  - 10.11648/j.cmr.20200901.14
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 20
EP  - 24
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20200901.14
AB  - Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. We aimed to evaluate the complete blood count (CBC) and erythrocyte sedimentation rate (ESR) of confirmed extra-pulmonary tuberculosis (EPTB) patients attending clinic at the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu. A total of 90 confirmed extra-pulmonary tuberculosis patients consisting of male (n = 38) and female (n = 52), aged 15 to 60 years attending clinic participated in this study. CBC and ESR were analysed using Haematological Auto Analyzer and Westergren method respectively. Haemoglobin and haematocrit values across the three age groups (15-30, 31-45, 46-60 years) were significantly lower (p < 0.05) than the control value in both male and female extra-pulmonary tuberculosis patients. Erythrocyte sedimentation rate, white blood count, platelet and neutrophil values across the three were significantly higher (p < 0.05) than the control values in both male and female extra-pulmonary tuberculosis patients. Extra-pulmonary tuberculosis was observed more in females than the males and was relatively higher in older patients (above 46 years) than younger patients (below 46 years). This study was able to show that different haematological parameters such as haemoglobin, haematocrit, Erythrocyte sedimentation rate, white blood count, platelet and neutrophil could serve as hallmark and help in early diagnosis of extra-pulmonary tuberculosis.
VL  - 9
IS  - 1
ER  -

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Author Information

Silas Anayochukwu Ufelle

Department of Medical Laboratory Sciences, University of Nigeria Enugu Campus, Enugu, Nigeria
Kenechukwu Chibuike Onyekwelu

Department of Medical Biochemistry, University of Nigeria Enugu Campus, Enugu, Nigeria
Peter Uwadiegwu Achukwu

Department of Medical Laboratory Sciences, University of Nigeria Enugu Campus, Enugu, Nigeria
Augustine Chidi Ndubisi

Department of Medical Biochemistry, University of Nigeria Enugu Campus, Enugu, Nigeria
Richard Chukwunonye Ezeh

Department of Medical Biochemistry, ESUT College of Medicine, Parklane, Nigeria
Lorreta Nwakaego Nwokolo

Department of Medical Biochemistry, University of Nigeria Enugu Campus, Enugu, Nigeria

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APA Style

Silas Anayochukwu Ufelle, Kenechukwu Chibuike Onyekwelu, Peter Uwadiegwu Achukwu, Augustine Chidi Ndubisi, Richard Chukwunonye Ezeh, et al. (2020). Haematological Profiles of Patients with Extra-pulmonary Tuberculosis. Clinical Medicine Research, 9(1), 20-24. https://doi.org/10.11648/j.cmr.20200901.14

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ACS Style

Silas Anayochukwu Ufelle; Kenechukwu Chibuike Onyekwelu; Peter Uwadiegwu Achukwu; Augustine Chidi Ndubisi; Richard Chukwunonye Ezeh, et al. Haematological Profiles of Patients with Extra-pulmonary Tuberculosis. Clin. Med. Res. 2020, 9(1), 20-24. doi: 10.11648/j.cmr.20200901.14

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AMA Style

Silas Anayochukwu Ufelle, Kenechukwu Chibuike Onyekwelu, Peter Uwadiegwu Achukwu, Augustine Chidi Ndubisi, Richard Chukwunonye Ezeh, et al. Haematological Profiles of Patients with Extra-pulmonary Tuberculosis. Clin Med Res. 2020;9(1):20-24. doi: 10.11648/j.cmr.20200901.14

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@article{10.11648/j.cmr.20200901.14,
  author = {Silas Anayochukwu Ufelle and Kenechukwu Chibuike Onyekwelu and Peter Uwadiegwu Achukwu and Augustine Chidi Ndubisi and Richard Chukwunonye Ezeh and Lorreta Nwakaego Nwokolo},
  title = {Haematological Profiles of Patients with Extra-pulmonary Tuberculosis},
  journal = {Clinical Medicine Research},
  volume = {9},
  number = {1},
  pages = {20-24},
  doi = {10.11648/j.cmr.20200901.14},
  url = {https://doi.org/10.11648/j.cmr.20200901.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20200901.14},
  abstract = {Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. We aimed to evaluate the complete blood count (CBC) and erythrocyte sedimentation rate (ESR) of confirmed extra-pulmonary tuberculosis (EPTB) patients attending clinic at the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu. A total of 90 confirmed extra-pulmonary tuberculosis patients consisting of male (n = 38) and female (n = 52), aged 15 to 60 years attending clinic participated in this study. CBC and ESR were analysed using Haematological Auto Analyzer and Westergren method respectively. Haemoglobin and haematocrit values across the three age groups (15-30, 31-45, 46-60 years) were significantly lower (p < 0.05) than the control value in both male and female extra-pulmonary tuberculosis patients. Erythrocyte sedimentation rate, white blood count, platelet and neutrophil values across the three were significantly higher (p < 0.05) than the control values in both male and female extra-pulmonary tuberculosis patients. Extra-pulmonary tuberculosis was observed more in females than the males and was relatively higher in older patients (above 46 years) than younger patients (below 46 years). This study was able to show that different haematological parameters such as haemoglobin, haematocrit, Erythrocyte sedimentation rate, white blood count, platelet and neutrophil could serve as hallmark and help in early diagnosis of extra-pulmonary tuberculosis.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Haematological Profiles of Patients with Extra-pulmonary Tuberculosis
AU  - Silas Anayochukwu Ufelle
AU  - Kenechukwu Chibuike Onyekwelu
AU  - Peter Uwadiegwu Achukwu
AU  - Augustine Chidi Ndubisi
AU  - Richard Chukwunonye Ezeh
AU  - Lorreta Nwakaego Nwokolo
Y1  - 2020/02/18
PY  - 2020
N1  - https://doi.org/10.11648/j.cmr.20200901.14
DO  - 10.11648/j.cmr.20200901.14
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 20
EP  - 24
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20200901.14
AB  - Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. We aimed to evaluate the complete blood count (CBC) and erythrocyte sedimentation rate (ESR) of confirmed extra-pulmonary tuberculosis (EPTB) patients attending clinic at the University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla, Enugu. A total of 90 confirmed extra-pulmonary tuberculosis patients consisting of male (n = 38) and female (n = 52), aged 15 to 60 years attending clinic participated in this study. CBC and ESR were analysed using Haematological Auto Analyzer and Westergren method respectively. Haemoglobin and haematocrit values across the three age groups (15-30, 31-45, 46-60 years) were significantly lower (p < 0.05) than the control value in both male and female extra-pulmonary tuberculosis patients. Erythrocyte sedimentation rate, white blood count, platelet and neutrophil values across the three were significantly higher (p < 0.05) than the control values in both male and female extra-pulmonary tuberculosis patients. Extra-pulmonary tuberculosis was observed more in females than the males and was relatively higher in older patients (above 46 years) than younger patients (below 46 years). This study was able to show that different haematological parameters such as haemoglobin, haematocrit, Erythrocyte sedimentation rate, white blood count, platelet and neutrophil could serve as hallmark and help in early diagnosis of extra-pulmonary tuberculosis.
VL  - 9
IS  - 1
ER  -

Copy | Download