Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia

Tsegahun Asfaw; Moges Lewetegn; Helen Tariku

doi:doi:10.11648/j.cmr.20180705.11

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Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia

Tsegahun Asfaw, Moges Lewetegn, Helen Tariku

Published in Clinical Medicine Research (Volume 7, Issue 5)

Received: 27 August 2018 Accepted: 10 September 2018 Published: 24 October 2018

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Abstract

Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staﬀ capacity building and increasing public awareness.

Published in	Clinical Medicine Research (Volume 7, Issue 5)
DOI	10.11648/j.cmr.20180705.11
Page(s)	97-102
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Trends, Treatment Outcomes, Tuberculosis

References

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[2]	World Health Organization, Global Tuberculosis Control report: WHO Report 2014, WHO/HTM/TB/ 2014. 08, World Health Organization, Geneva, Switzerland, 2014.
[3]	World Health Organization, Global Tuberculosis Control: WHO Report 2011, WHO/HTM/TB/ 2011.16, World Health Organization, Geneva, Switzerland, 2011.
[4]	Federal Democratic Republic of Ethiopia, Ministry of Health (FMOH) (2009) TB/ HIV implementation guideline, Addis Ababa, Ethiopia.
[5]	Ai X, Men K, Guo L et al., Factors associated with low cure rate of tuberculosis in remote poor areas of Shaanxi Province, China: a case control study, BMC Public Health, 2010 vol. 10, article 112.
[6]	Berhe G, Enquselassie F, and Aseﬀa A, Treatment outcome of smear-positive pulmonary tuberculosis patients in Tigray Region, Northern Ethiopia, BMC Public Health, 2012, vol. 12, p. 537.
[7]	Demeke D, Legesse M, Bati J. Trend of Tuberculosis and Treatment Outcomes in Gambella Region with Special Emphasize on Gambella Regional Hospital, Western Ethiopia. J Mycobac Dis, 2013, 3: 130.
[8]	Nigatu T, Abraha M (2010) Epidemiological analysis of tuberculosis trends in Ethiopia Tüberküloz, 2010; 58: 375-384.
[9]	World Health Organization: Global Plan to Stop TB 2011-2015. Davos, Switzerland: WHO; 2006.
[10]	Tessema B, Muche A, Bekele A, Reissig D, Emmrich F, and Sack U. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia. A five year retrospective study, BMC Public Health, 2009; vol. 9, article 371.
[11]	Biadglegne F, Anagaw B, Debebe T et al., A retrospective study on the outcomes of tuberculosis treatment in Felege Hiwot Referral Hospital, Northwest Ethiopia, International Journal of Medical Sciences, 2013; vol. 5, no. 2, pp. 85–91.
[12]	Ramos JM, Reyes F, and Tesfamariam A, Childhood and adult tuberculosis in a rural hospital in Southeast Ethiopia: a ten-year retrospective study, BMC Public Health, 2010; vol. 10, article 215.
[13]	World Health Organization, G Global Tuberculosis Report 2012, WHO, Geneva, Switzerland, 2012.
[14]	Sisay S, Mengistu B, Erku W, WoldeyohannesD. Directly Observed Treatment Short-course (DOTS) for tuberculosis control program in Gambella Regional State, Ethiopia: ten years’ experience. BMC Res Notes, 2014;7(44):1756-0500.
[15]	Belete G, Gobena A, Girmay M, Sibhatu B. Treatment outcome of tuberculosis patients under directly observed treatment in Addis Ababa, Ethiopia. Braz J Infect Dis, 2013;17(5):521-528.
[16]	Belay T, Abebe M, Assegedech B, Dieter R, Frank E, Ulrich S. Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia: Afive-year retrospective study. BMC Public Health, 2009; 9(371):1471-2458.
[17]	Ukwaja KN, Modebe O, Igwenyi C, Alobu I. The economic burden of tuberculosis care for patients and households in Africa: a systematic review. The International Journal of Tuberculosis and Lung Disease, 2012; 16(6); 733-739.

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APA Style

Tsegahun Asfaw, Moges Lewetegn, Helen Tariku. (2018). Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clinical Medicine Research, 7(5), 97-102. https://doi.org/10.11648/j.cmr.20180705.11

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ACS Style

Tsegahun Asfaw; Moges Lewetegn; Helen Tariku. Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clin. Med. Res. 2018, 7(5), 97-102. doi: 10.11648/j.cmr.20180705.11

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AMA Style

Tsegahun Asfaw, Moges Lewetegn, Helen Tariku. Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clin Med Res. 2018;7(5):97-102. doi: 10.11648/j.cmr.20180705.11

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@article{10.11648/j.cmr.20180705.11,
  author = {Tsegahun Asfaw and Moges Lewetegn and Helen Tariku},
  title = {Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia},
  journal = {Clinical Medicine Research},
  volume = {7},
  number = {5},
  pages = {97-102},
  doi = {10.11648/j.cmr.20180705.11},
  url = {https://doi.org/10.11648/j.cmr.20180705.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20180705.11},
  abstract = {Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staﬀ capacity building and increasing public awareness.},
 year = {2018}
}

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TY  - JOUR
T1  - Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia
AU  - Tsegahun Asfaw
AU  - Moges Lewetegn
AU  - Helen Tariku
Y1  - 2018/10/24
PY  - 2018
N1  - https://doi.org/10.11648/j.cmr.20180705.11
DO  - 10.11648/j.cmr.20180705.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 97
EP  - 102
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20180705.11
AB  - Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staﬀ capacity building and increasing public awareness.
VL  - 7
IS  - 5
ER  -

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Author Information

Tsegahun Asfaw

Department of Medical Laboratory Science, Debre Berhan University, Debre Berhan, Ethiopia
Moges Lewetegn

Department of Medical Laboratory Science, Debre Berhan University, Debre Berhan, Ethiopia
Helen Tariku

Department of Medical Laboratory Science, Debre Berhan University, Debre Berhan, Ethiopia

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APA Style

Tsegahun Asfaw, Moges Lewetegn, Helen Tariku. (2018). Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clinical Medicine Research, 7(5), 97-102. https://doi.org/10.11648/j.cmr.20180705.11

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ACS Style

Tsegahun Asfaw; Moges Lewetegn; Helen Tariku. Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clin. Med. Res. 2018, 7(5), 97-102. doi: 10.11648/j.cmr.20180705.11

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AMA Style

Tsegahun Asfaw, Moges Lewetegn, Helen Tariku. Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia. Clin Med Res. 2018;7(5):97-102. doi: 10.11648/j.cmr.20180705.11

Copy | Download

@article{10.11648/j.cmr.20180705.11,
  author = {Tsegahun Asfaw and Moges Lewetegn and Helen Tariku},
  title = {Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia},
  journal = {Clinical Medicine Research},
  volume = {7},
  number = {5},
  pages = {97-102},
  doi = {10.11648/j.cmr.20180705.11},
  url = {https://doi.org/10.11648/j.cmr.20180705.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20180705.11},
  abstract = {Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staﬀ capacity building and increasing public awareness.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Trends and Treatment Outcomes of Tuberculosis in Debre Berhan Referral Hospital, Debre Drehan, Ethiopia
AU  - Tsegahun Asfaw
AU  - Moges Lewetegn
AU  - Helen Tariku
Y1  - 2018/10/24
PY  - 2018
N1  - https://doi.org/10.11648/j.cmr.20180705.11
DO  - 10.11648/j.cmr.20180705.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 97
EP  - 102
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20180705.11
AB  - Tuberculosis (TB) remains major Public health problem and among the top ten leading causes of human deaths worldwide. Moreover, TB is the leading cause of morbidity, one of the three major causes for hospital admission, and the second killer next to malaria in Ethiopia. Early diagnosis, effective treatment and continues assessment of treatment outcome are important to improve TB management program. Retrospective study design was conducted to assess trend and treatment outcomes of TB in Debre Berhan referral hospital. 4 years (2014 to 2017) TB case records was reviewed with standard check list and entered in to EpiData 3.1 and analyzed using SPSS version 16. Among the total registered TB patients with complete record (n=506), 256(50.6%) were males and 250(49.4%) Female. The treatment cured rate varies from 23.29% in 2006 E.C to 47.45% in 2007 E.C, whereas treatment completed varies from 46.91% in 2007 E.C to 67.08% in 2009 E.C. Majority of the smear-positive pulmonary tuberculosis patients 183 (97.3%) were cured at the end of their anti-TB treatment. The proportion of HIV co-infection among TB patients was 21.3%. However, overall cure rate was nearly the same in both HIV positive and negative patients. As conclusion majority of the smear-positive pulmonary tuberculosis patients were cured at the end of their anti-TB treatment. There was also a continuous increment of treatment success rate, indicating that the hospital is within the track of WHO target currently. However the proportion of HIV co-infection among TB patients was higher which signifies the urgent need for staﬀ capacity building and increasing public awareness.
VL  - 7
IS  - 5
ER  -

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