Background: Neurogenic or neuropathic bladder is defined as any defective functioning of the bladder caused by impaired innervations. Pernicious anemia is a rare cause of neurogenic bladder and it is often accompanied by other neurological manifestations. The standard treatment is based on parenteral vitamin administration. We report a unique case of pernicious anemia revealed by a neurogenic bladder succefully managed by vitamin B12 administration. Case presentation: A 45-year-old man presented with lower urinary tract symptoms (LUTS) with urine retentions. The patient was an important postvoid residual volume. The uroflowmetry result of the patient was low. Cystoscopy reveals a normal urethra, prostatic fossa, and bladder. Urodynamic testing demonstrated a failure voiding bladder. The diagnostic of pernicious anemia was suspected in laboratory exams which have showed megaloblastic anemia and Serum antibodies to gastric parietal cells, the diagnostic was confirmed by gastric biopsy. The patient was traited by oral administration of vitamin B12. At his 6 months follow-up, clinical symptoms had improved, and there was no significant postvoid residual (PVR). Conclusion: The vesicosphincteriens disorders in pernicious anemia are very little detail in the literature .our case is to our knowledge the first to have urinary voiding dysfunction as the only symptom of pernicious anemia with spectacular improvement after vitamin B12 administration.
| Published in | Clinical Medicine Research (Volume 3, Issue 3) |
| DOI | 10.11648/j.cmr.20140303.12 |
| Page(s) | 61-64 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2014. Published by Science Publishing Group |
Pernicious Anemia, Vesicosphincteriens Disorders, Vitamin B12, Postvoid Residual (PVR)
| [1] | Stedman’s online medical dictionary. Lippincottt Williams & Wilkins. http://www.stedmans.com. Accessed July 23, 2007. |
| [2] | Curtis LA, Dolan TS, Cespedes RD. Acute urinary retention and urinary incontinence. Emerg Med Clin North Am. 2001;19(3):591-619. |
| [3] | Zittoun J. [Biermer's disease] Rev Prat 2001; 51: 1542-1546 |
| [4] | Meecham J, Jones EW. Addison's disease and Addisonian anaemia. Lancet 1967; 1: 535-538 |
| [5] | Wintrobe MM, Lee GR, Boggs DR, Bithell TC, Foerster J,Athens JW, Lukens JN. Megaloblastic and nonmegaloblastic macrocytic anemias. In: Wintrobe MM, Lee GR, Boggs DR, Bithell TC, Foerster J, Athens JW, Lukens JN, editors. Clinical hematology. 8th ed. Philadelphia: Lea & Febiger, 1981: 559-604 |
| [6] | Lee EL, Feldman M. Gastritis and other gastropathies. In: Feldman M, Friedman LS, Sleisenger MH, editors. Sleisenger & Fordtran's gastrointestinal and liver disease: pathophysiology, diagnosis, management. 7th ed. Philadelphia: Saunders, 2002: 810-827 |
| [7] | Babior BM. Erythrocyte disorders: Anemias related to disturbance of DNA synthesis (megaloblastic anemias). In: Williams JW, Beutler E, Erslev AJ, Lichtman MA, editors. Hematology. 4th ed. New York: McGraw-Hill, 1998: 453-481 |
| [8] | Toh BH, Gleeson PA, Whittingham S, van Driel IR. Autoimmune gastritis and pernicious anemia. In: Rose NR, Mackay IR, editors. The autoimmune diseases. 3rd ed. St. Louis, MO: Academic Press, 1998: 459-476 |
| [9] | D'Elios MM, Appelmelk BJ, Amedei A, Bergman MP, Del Prete G. Gastric autoimmunity: the role of Helicobacter pylori and molecular mimicry. Trends Mol Med 2004; 10: 316-323 |
| [10] | FARQUHARSON, R. F., AND GRAHAM, D.: Liver therapy in the treatment of subacute combined degeneration of the cord. Canadian M. A. J. 23: 137, 1930. |
| [11] | HYLAND, H. H., AND FARQUHARSON, R. F.: Subacute combined degeneration of the spinal cord in pernicious anemia. Arch. Neurol. & Psychiat. 36: ii66, 1936. |
| [12] | UNGLEY, C. C., AND SUZMAN, M. M.: Subacute combined degeneration of the cord: symptomatology and effects of liver therapy. Brain 52.’ 2.71, 192.9. |
| [13] | Hvas AM, Nexo E. Diagnosis and treatment of vitamin B12 deficiency--an update. Haematologica 2006; 91: 1506-1512 |
APA Style
Omar Riyach, Mustapha Ahsaini, Mohammed Fadl Tazi, Jalal Eddine El Ammari, Mohammed Jamal El Fassi, et al. (2014). Neurogenic Bladder Revealing a Pernicious Anemia: One Case Report and Literature Review. Clinical Medicine Research, 3(3), 61-64. https://doi.org/10.11648/j.cmr.20140303.12
ACS Style
Omar Riyach; Mustapha Ahsaini; Mohammed Fadl Tazi; Jalal Eddine El Ammari; Mohammed Jamal El Fassi, et al. Neurogenic Bladder Revealing a Pernicious Anemia: One Case Report and Literature Review. Clin. Med. Res. 2014, 3(3), 61-64. doi: 10.11648/j.cmr.20140303.12
AMA Style
Omar Riyach, Mustapha Ahsaini, Mohammed Fadl Tazi, Jalal Eddine El Ammari, Mohammed Jamal El Fassi, et al. Neurogenic Bladder Revealing a Pernicious Anemia: One Case Report and Literature Review. Clin Med Res. 2014;3(3):61-64. doi: 10.11648/j.cmr.20140303.12
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Download@article{10.11648/j.cmr.20140303.12,
author = {Omar Riyach and Mustapha Ahsaini and Mohammed Fadl Tazi and Jalal Eddine El Ammari and Mohammed Jamal El Fassi and Abdelhak Khallouk and Moulay Hassan Farih},
title = {Neurogenic Bladder Revealing a Pernicious Anemia: One Case Report and Literature Review},
journal = {Clinical Medicine Research},
volume = {3},
number = {3},
pages = {61-64},
doi = {10.11648/j.cmr.20140303.12},
url = {https://doi.org/10.11648/j.cmr.20140303.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20140303.12},
abstract = {Background: Neurogenic or neuropathic bladder is defined as any defective functioning of the bladder caused by impaired innervations. Pernicious anemia is a rare cause of neurogenic bladder and it is often accompanied by other neurological manifestations. The standard treatment is based on parenteral vitamin administration. We report a unique case of pernicious anemia revealed by a neurogenic bladder succefully managed by vitamin B12 administration. Case presentation: A 45-year-old man presented with lower urinary tract symptoms (LUTS) with urine retentions. The patient was an important postvoid residual volume. The uroflowmetry result of the patient was low. Cystoscopy reveals a normal urethra, prostatic fossa, and bladder. Urodynamic testing demonstrated a failure voiding bladder. The diagnostic of pernicious anemia was suspected in laboratory exams which have showed megaloblastic anemia and Serum antibodies to gastric parietal cells, the diagnostic was confirmed by gastric biopsy. The patient was traited by oral administration of vitamin B12. At his 6 months follow-up, clinical symptoms had improved, and there was no significant postvoid residual (PVR). Conclusion: The vesicosphincteriens disorders in pernicious anemia are very little detail in the literature .our case is to our knowledge the first to have urinary voiding dysfunction as the only symptom of pernicious anemia with spectacular improvement after vitamin B12 administration.},
year = {2014}
}
TY - JOUR T1 - Neurogenic Bladder Revealing a Pernicious Anemia: One Case Report and Literature Review AU - Omar Riyach AU - Mustapha Ahsaini AU - Mohammed Fadl Tazi AU - Jalal Eddine El Ammari AU - Mohammed Jamal El Fassi AU - Abdelhak Khallouk AU - Moulay Hassan Farih Y1 - 2014/04/30 PY - 2014 N1 - https://doi.org/10.11648/j.cmr.20140303.12 DO - 10.11648/j.cmr.20140303.12 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 61 EP - 64 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20140303.12 AB - Background: Neurogenic or neuropathic bladder is defined as any defective functioning of the bladder caused by impaired innervations. Pernicious anemia is a rare cause of neurogenic bladder and it is often accompanied by other neurological manifestations. The standard treatment is based on parenteral vitamin administration. We report a unique case of pernicious anemia revealed by a neurogenic bladder succefully managed by vitamin B12 administration. Case presentation: A 45-year-old man presented with lower urinary tract symptoms (LUTS) with urine retentions. The patient was an important postvoid residual volume. The uroflowmetry result of the patient was low. Cystoscopy reveals a normal urethra, prostatic fossa, and bladder. Urodynamic testing demonstrated a failure voiding bladder. The diagnostic of pernicious anemia was suspected in laboratory exams which have showed megaloblastic anemia and Serum antibodies to gastric parietal cells, the diagnostic was confirmed by gastric biopsy. The patient was traited by oral administration of vitamin B12. At his 6 months follow-up, clinical symptoms had improved, and there was no significant postvoid residual (PVR). Conclusion: The vesicosphincteriens disorders in pernicious anemia are very little detail in the literature .our case is to our knowledge the first to have urinary voiding dysfunction as the only symptom of pernicious anemia with spectacular improvement after vitamin B12 administration. VL - 3 IS - 3 ER -
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