Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk

Sarah Mangiafico; Ines Paola Monte; Vincenzo Lavanco; Lucio Raffaello Tropea; Antonio Andrea Arcidiacono; Maria Concetta di Pasqua; Letizia Santonoceto; Giovanni Millan; Corrado Tamburino

doi:doi:10.11648/j.cmr.20130204.12

Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk

Sarah Mangiafico, Ines Paola Monte, Vincenzo Lavanco, Lucio Raffaello Tropea, Antonio Andrea Arcidiacono, Maria Concetta di Pasqua, Letizia Santonoceto, Giovanni Millan, Corrado Tamburino

Published in Clinical Medicine Research (Volume 2, Issue 4)

Received: 13 May 2013 Published: 20 June 2013

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Abstract

Atrial septal aneurysm when associated to other cardiac abnormalities, such as patent foramen ovale, Chiari network or Eustachian Membrane, is a well-known recognised risk factor for cerebral embolism. Aim of study is to assess if isolated atrial septal aneurysm could be considered statistically related to cryptogenic stroke, considering the strong clinical impact that this association could have on these patients outcome. 579 patients were investigated for a suspected patent foramen ovale using transthoracic echocardiography, in order to evaluate the presence of atrial septal aneurysm and to identify other potential cardiac embolic sources. The patients with atrial septal aneurysm underwent transcranic echodoppler and transoesophageal echocardiography examination with contrast solution during Valsalva manoeuvre.209/579 (36%) patients where we made diagnosis of atrial septal aneurysm. In this cohort of patients transcranic echodoppler showed a patent foramen ovale in 114/209 (54%), whereas transoesophageal echocardiography in 111/209 (53%); 6/114 (5%) pa-tients with a positive transcranic echodoppler had a normal transoesophageal echocardiography examination and 3/95 (3%) with normal transcranic echodoppler had a positive transoesophageal echocardiography. Transcranic echodoppler vs. transoesophageal echocardiography sensibility was 97% and specificity 94%. Only 13/98 (13%) of patients with isolated atrial septal aneurysm and 23/111 (26%) with patent foramen ovale had history of cryptogenic stroke. According to our data, isolated atrial septal aneurysm could not be considered an independent risk factor for cryptogenic stroke.

Published in	Clinical Medicine Research (Volume 2, Issue 4)
DOI	10.11648/j.cmr.20130204.12
Page(s)	48-52
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Atrial Septum Aneurysm, Stroke, Echocardiography

References

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[5]	Ghosh S, Ghosh AK, Ghosh SK. Patent foramen ovale and atrial septal aneurysm in cryptogenic stroke. Postgrad Med J 2007; 83: 173–177
[6]	Davison P, Clift PF, Steeds RP. The role of echocardiography in diagnosis, monitoring closure and post-procedural assessment of patent foramen ovale. Eur J Echocardiogr 2010; 11 (10): i27-34
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[15]	Mangiafico S, Scandura S, Ussia GP, Privitera A, Capodanno D, Petralia A, Tamburino C. Transesophageal echocardiography and transcranial color-doppler: indipendent or complementary diagnostic tests for cardiologists in the detection of patent foramen ovale? J Cardiovasc Med 2009; 10:143-148.
[16]	Agmon Y, Khandheria BK, Meissner I, Gentile F, Whisnant JP, Sicks JD, O’Fallon M, Covalt J, Wiebers D, Seward JB . Frequency of atrial septal aneurysms in patients with cerebral ischemic events. Circulation 1999; 99: 1942–1944
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APA Style

Sarah Mangiafico, Ines Paola Monte, Vincenzo Lavanco, Lucio Raffaello Tropea, Antonio Andrea Arcidiacono, et al. (2013). Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk. Clinical Medicine Research, 2(4), 48-52. https://doi.org/10.11648/j.cmr.20130204.12

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ACS Style

Sarah Mangiafico; Ines Paola Monte; Vincenzo Lavanco; Lucio Raffaello Tropea; Antonio Andrea Arcidiacono, et al. Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk. Clin. Med. Res. 2013, 2(4), 48-52. doi: 10.11648/j.cmr.20130204.12

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AMA Style

Sarah Mangiafico, Ines Paola Monte, Vincenzo Lavanco, Lucio Raffaello Tropea, Antonio Andrea Arcidiacono, et al. Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk. Clin Med Res. 2013;2(4):48-52. doi: 10.11648/j.cmr.20130204.12

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@article{10.11648/j.cmr.20130204.12,
  author = {Sarah Mangiafico and Ines Paola Monte and Vincenzo Lavanco and Lucio Raffaello Tropea and Antonio Andrea Arcidiacono and Maria Concetta di Pasqua and Letizia Santonoceto and Giovanni Millan and Corrado Tamburino},
  title = {Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk},
  journal = {Clinical Medicine Research},
  volume = {2},
  number = {4},
  pages = {48-52},
  doi = {10.11648/j.cmr.20130204.12},
  url = {https://doi.org/10.11648/j.cmr.20130204.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20130204.12},
  abstract = {Atrial septal aneurysm when associated to other cardiac abnormalities, such as patent foramen ovale, Chiari network or Eustachian Membrane, is a well-known recognised risk factor for cerebral embolism. Aim of study is to assess if isolated atrial septal aneurysm could be considered statistically related to cryptogenic stroke, considering the strong clinical impact that this association could have on these patients outcome. 579 patients were investigated for a suspected patent foramen ovale using transthoracic echocardiography, in order to evaluate the presence of atrial septal aneurysm and to identify other potential cardiac embolic sources. The patients with atrial septal aneurysm underwent transcranic echodoppler and transoesophageal echocardiography examination with contrast solution during Valsalva manoeuvre.209/579 (36%) patients where we made diagnosis of atrial septal aneurysm. In this cohort of patients transcranic echodoppler showed a patent foramen ovale in 114/209 (54%), whereas transoesophageal echocardiography in 111/209 (53%); 6/114 (5%) pa-tients with a positive transcranic echodoppler had a normal transoesophageal echocardiography examination and 3/95 (3%) with normal transcranic echodoppler had a positive transoesophageal echocardiography. Transcranic echodoppler vs. transoesophageal echocardiography sensibility was 97% and specificity 94%. Only 13/98 (13%) of patients with isolated atrial septal aneurysm and 23/111 (26%) with patent foramen ovale had history of cryptogenic stroke. According to our data, isolated atrial septal aneurysm could not be considered an independent risk factor for cryptogenic stroke.},
 year = {2013}
}

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TY  - JOUR
T1  - Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk
AU  - Sarah Mangiafico
AU  - Ines Paola Monte
AU  - Vincenzo Lavanco
AU  - Lucio Raffaello Tropea
AU  - Antonio Andrea Arcidiacono
AU  - Maria Concetta di Pasqua
AU  - Letizia Santonoceto
AU  - Giovanni Millan
AU  - Corrado Tamburino
Y1  - 2013/06/20
PY  - 2013
N1  - https://doi.org/10.11648/j.cmr.20130204.12
DO  - 10.11648/j.cmr.20130204.12
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 48
EP  - 52
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20130204.12
AB  - Atrial septal aneurysm when associated to other cardiac abnormalities, such as patent foramen ovale, Chiari network or Eustachian Membrane, is a well-known recognised risk factor for cerebral embolism. Aim of study is to assess if isolated atrial septal aneurysm could be considered statistically related to cryptogenic stroke, considering the strong clinical impact that this association could have on these patients outcome. 579 patients were investigated for a suspected patent foramen ovale using transthoracic echocardiography, in order to evaluate the presence of atrial septal aneurysm and to identify other potential cardiac embolic sources. The patients with atrial septal aneurysm underwent transcranic echodoppler and transoesophageal echocardiography examination with contrast solution during Valsalva manoeuvre.209/579 (36%) patients where we made diagnosis of atrial septal aneurysm. In this cohort of patients transcranic echodoppler showed a patent foramen ovale in 114/209 (54%), whereas transoesophageal echocardiography in 111/209 (53%); 6/114 (5%) pa-tients with a positive transcranic echodoppler had a normal transoesophageal echocardiography examination and 3/95 (3%) with normal transcranic echodoppler had a positive transoesophageal echocardiography. Transcranic echodoppler vs. transoesophageal echocardiography sensibility was 97% and specificity 94%. Only 13/98 (13%) of patients with isolated atrial septal aneurysm and 23/111 (26%) with patent foramen ovale had history of cryptogenic stroke. According to our data, isolated atrial septal aneurysm could not be considered an independent risk factor for cryptogenic stroke.
VL  - 2
IS  - 4
ER  -

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Author Information

Sarah Mangiafico

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Ines Paola Monte

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Vincenzo Lavanco

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Lucio Raffaello Tropea

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Antonio Andrea Arcidiacono

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Maria Concetta di Pasqua

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Letizia Santonoceto

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Giovanni Millan

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy
Corrado Tamburino

Dept, Cardio-Thoraco-Vascular, AOU Policlinic University of Catania, Catania, Italy

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Plain Text BibTeX RIS

APA Style

Sarah Mangiafico, Ines Paola Monte, Vincenzo Lavanco, Lucio Raffaello Tropea, Antonio Andrea Arcidiacono, et al. (2013). Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk. Clinical Medicine Research, 2(4), 48-52. https://doi.org/10.11648/j.cmr.20130204.12

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ACS Style

Sarah Mangiafico; Ines Paola Monte; Vincenzo Lavanco; Lucio Raffaello Tropea; Antonio Andrea Arcidiacono, et al. Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk. Clin. Med. Res. 2013, 2(4), 48-52. doi: 10.11648/j.cmr.20130204.12

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AMA Style

Sarah Mangiafico, Ines Paola Monte, Vincenzo Lavanco, Lucio Raffaello Tropea, Antonio Andrea Arcidiacono, et al. Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk. Clin Med Res. 2013;2(4):48-52. doi: 10.11648/j.cmr.20130204.12

Copy | Download

@article{10.11648/j.cmr.20130204.12,
  author = {Sarah Mangiafico and Ines Paola Monte and Vincenzo Lavanco and Lucio Raffaello Tropea and Antonio Andrea Arcidiacono and Maria Concetta di Pasqua and Letizia Santonoceto and Giovanni Millan and Corrado Tamburino},
  title = {Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk},
  journal = {Clinical Medicine Research},
  volume = {2},
  number = {4},
  pages = {48-52},
  doi = {10.11648/j.cmr.20130204.12},
  url = {https://doi.org/10.11648/j.cmr.20130204.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20130204.12},
  abstract = {Atrial septal aneurysm when associated to other cardiac abnormalities, such as patent foramen ovale, Chiari network or Eustachian Membrane, is a well-known recognised risk factor for cerebral embolism. Aim of study is to assess if isolated atrial septal aneurysm could be considered statistically related to cryptogenic stroke, considering the strong clinical impact that this association could have on these patients outcome. 579 patients were investigated for a suspected patent foramen ovale using transthoracic echocardiography, in order to evaluate the presence of atrial septal aneurysm and to identify other potential cardiac embolic sources. The patients with atrial septal aneurysm underwent transcranic echodoppler and transoesophageal echocardiography examination with contrast solution during Valsalva manoeuvre.209/579 (36%) patients where we made diagnosis of atrial septal aneurysm. In this cohort of patients transcranic echodoppler showed a patent foramen ovale in 114/209 (54%), whereas transoesophageal echocardiography in 111/209 (53%); 6/114 (5%) pa-tients with a positive transcranic echodoppler had a normal transoesophageal echocardiography examination and 3/95 (3%) with normal transcranic echodoppler had a positive transoesophageal echocardiography. Transcranic echodoppler vs. transoesophageal echocardiography sensibility was 97% and specificity 94%. Only 13/98 (13%) of patients with isolated atrial septal aneurysm and 23/111 (26%) with patent foramen ovale had history of cryptogenic stroke. According to our data, isolated atrial septal aneurysm could not be considered an independent risk factor for cryptogenic stroke.},
 year = {2013}
}

Copy | Download

TY  - JOUR
T1  - Atrial Septal Aneurysm Is Always Linked To Right-Left Shunt and Cardio embolic Risk
AU  - Sarah Mangiafico
AU  - Ines Paola Monte
AU  - Vincenzo Lavanco
AU  - Lucio Raffaello Tropea
AU  - Antonio Andrea Arcidiacono
AU  - Maria Concetta di Pasqua
AU  - Letizia Santonoceto
AU  - Giovanni Millan
AU  - Corrado Tamburino
Y1  - 2013/06/20
PY  - 2013
N1  - https://doi.org/10.11648/j.cmr.20130204.12
DO  - 10.11648/j.cmr.20130204.12
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 48
EP  - 52
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20130204.12
AB  - Atrial septal aneurysm when associated to other cardiac abnormalities, such as patent foramen ovale, Chiari network or Eustachian Membrane, is a well-known recognised risk factor for cerebral embolism. Aim of study is to assess if isolated atrial septal aneurysm could be considered statistically related to cryptogenic stroke, considering the strong clinical impact that this association could have on these patients outcome. 579 patients were investigated for a suspected patent foramen ovale using transthoracic echocardiography, in order to evaluate the presence of atrial septal aneurysm and to identify other potential cardiac embolic sources. The patients with atrial septal aneurysm underwent transcranic echodoppler and transoesophageal echocardiography examination with contrast solution during Valsalva manoeuvre.209/579 (36%) patients where we made diagnosis of atrial septal aneurysm. In this cohort of patients transcranic echodoppler showed a patent foramen ovale in 114/209 (54%), whereas transoesophageal echocardiography in 111/209 (53%); 6/114 (5%) pa-tients with a positive transcranic echodoppler had a normal transoesophageal echocardiography examination and 3/95 (3%) with normal transcranic echodoppler had a positive transoesophageal echocardiography. Transcranic echodoppler vs. transoesophageal echocardiography sensibility was 97% and specificity 94%. Only 13/98 (13%) of patients with isolated atrial septal aneurysm and 23/111 (26%) with patent foramen ovale had history of cryptogenic stroke. According to our data, isolated atrial septal aneurysm could not be considered an independent risk factor for cryptogenic stroke.
VL  - 2
IS  - 4
ER  -

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