Although not common, postpartum and post-abortion infections caused by clostridia can be severe. Clostridial uterine infections start as localized chorioamnionitis as a result of an infection from the fetus and/or placental tissues. The infection may spread to the uterine wall and endometrial tissues, and, in the most severe cases, uterine necrosis accompanied by sepsis ensues. In this paper we report the presence of Clostridium perfringens isolated from blood culture and placental specimen after the termination of a 29 gestational week pregnancy. The woman had a history of having omphaloceled fetus and premature membrane rupture. Fetal omphalocele is a congenital defect of the abdominal wall that allows some of the abdominal organs to protrude through it. In order to find the focus of infection, blood and plasental specimen of the patient were examined. Blood cultures of the patient were evaluated by the BACTEC 9120 system. The identification of the bacteria was performed conventionally and confirmed by the automatized API 20A system. Antibiotic susceptibility testing was performed by E-test according to the recommendations of Clinical Laboratory and Standards Institute (CLSI). Although Clostridium spp is rarely isolated from blood cultures, anaerobically evaluation of blood cultures in the infections of abdominal and genital sites could be life-saving, as in this report.
| Published in | Clinical Medicine Research (Volume 2, Issue 3) |
| DOI | 10.11648/j.cmr.20130203.12 |
| Page(s) | 29-31 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Clostridium Perfringens, Blood Culture, Placental Specimen, Fetal Omphalocel
| [1] | Onderdonk AB, Garrett WS. Gas gangrene and other Clostridium-associated diseses. Mandell, Douglas and Bennet’s Principle and Practice of Infectious Diseases, 7th edition (Eds: Mandell GL, Bennet JE, Dolin RD), Chapter 246, p.3103-9, Churchill Livingstone, Philadelphia, USA, 2010. |
| [2] | Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Suscebtibility Testing. 21st Informational Supplement. M100-S21, Vol 31, No 1, Table 2J (M02- M07: Anaerobes), Wayne, PA: Clinical and Laboratory Standards Institute, 2011. |
| [3] | Kleinrouweler CE, Kuijper CF, Zalen-Sprock MM et al. Characteristics and outcome and the omphalocele circumference/abdominal circumference ratio in prenatally diagnosed fetal omphalocele. Fetal Diagn Ther 2011; 30: 60-69. |
| [4] | Brantberg A, Blaas HGK, Haugens SE, Eik-Nes SH. Characteristics and outcome of 90 cases of fetal omphalocele. Ultrasound Obstet Gynecol 2005; 26: 527-537. |
| [5] | Tassin M, Descriaud C, Elie C, Debarge VH, Dumez Y, Perrotin F, Benachi A. Omphalocele in the first trimester: prediction of perinatal outcome. Prenatal Diagnosis 2013; 33, 497–501 |
| [6] | Fujita H, Nishimura S, Kurosawa S, Akiya I, Nakamura-Uchiyama F, Ohnishi K. Clinical and Epidemiological Features of Clostridium perfringens Bacteremia: A Review of 18 Cases over 8 Year-Period in a Tertiary Care Center in Metropolitan Tokyo Area in Japan. Intern Med 2010; 49: 2433-2437 |
| [7] | Myers G, Ngoi SS, Cennerazzo W, Harris L, DeCosse JJ. Clostridial septicemia in an urban hospital. Surg Gynecol Obstet. 1992; 174 (4):291-6. |
| [8] | Itzhak B. Anaerobic bacteria. "Cohen J, Powderly WG (eds):Infectious Diseases, Second edition, p.2265, Mosby, Elsevier,2004. |
| [9] | https://www.luriechildrens.org/en-us/care-services/conditions-treatments/institute-fetal-health/Pages/basics/fetal-general-surgery/fetal-omphalocele.aspx |
| [10] | Kasper D, Madoff LC. Gas gangrene and other Clostridial infections. "Harrison’s Infectious Diseases Kasper D, Fauci AS (eds), Chapter 42, p.438, McGraw-Hill Companies, USA, 2010. |
| [11] | Soper DE. Infections of the female pelvis. Mandell, Douglas and Bennet’s Principle and Practice of Infectious Diseases, 7th edition (Eds: Mandell GL, Bennet JE, Dolin RD), Chapter 108, p. 1511, Churchill Livingstone, Philadelphia, USA, 2010. |
APA Style
Nezahat Gurler, Lutfiye Oksuz, Bahar Yuksel, Recep Has. (2013). A Case of Clostridium Perfringens Sepsis in the 29 Week Pregnant Woman with Diagnosed Fetal Omphalosel. Clinical Medicine Research, 2(3), 29-31. https://doi.org/10.11648/j.cmr.20130203.12
ACS Style
Nezahat Gurler; Lutfiye Oksuz; Bahar Yuksel; Recep Has. A Case of Clostridium Perfringens Sepsis in the 29 Week Pregnant Woman with Diagnosed Fetal Omphalosel. Clin. Med. Res. 2013, 2(3), 29-31. doi: 10.11648/j.cmr.20130203.12
AMA Style
Nezahat Gurler, Lutfiye Oksuz, Bahar Yuksel, Recep Has. A Case of Clostridium Perfringens Sepsis in the 29 Week Pregnant Woman with Diagnosed Fetal Omphalosel. Clin Med Res. 2013;2(3):29-31. doi: 10.11648/j.cmr.20130203.12
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.cmr.20130203.12,
author = {Nezahat Gurler and Lutfiye Oksuz and Bahar Yuksel and Recep Has},
title = {A Case of Clostridium Perfringens Sepsis in the 29 Week Pregnant Woman with Diagnosed Fetal Omphalosel},
journal = {Clinical Medicine Research},
volume = {2},
number = {3},
pages = {29-31},
doi = {10.11648/j.cmr.20130203.12},
url = {https://doi.org/10.11648/j.cmr.20130203.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20130203.12},
abstract = {Although not common, postpartum and post-abortion infections caused by clostridia can be severe. Clostridial uterine infections start as localized chorioamnionitis as a result of an infection from the fetus and/or placental tissues. The infection may spread to the uterine wall and endometrial tissues, and, in the most severe cases, uterine necrosis accompanied by sepsis ensues. In this paper we report the presence of Clostridium perfringens isolated from blood culture and placental specimen after the termination of a 29 gestational week pregnancy. The woman had a history of having omphaloceled fetus and premature membrane rupture. Fetal omphalocele is a congenital defect of the abdominal wall that allows some of the abdominal organs to protrude through it. In order to find the focus of infection, blood and plasental specimen of the patient were examined. Blood cultures of the patient were evaluated by the BACTEC 9120 system. The identification of the bacteria was performed conventionally and confirmed by the automatized API 20A system. Antibiotic susceptibility testing was performed by E-test according to the recommendations of Clinical Laboratory and Standards Institute (CLSI). Although Clostridium spp is rarely isolated from blood cultures, anaerobically evaluation of blood cultures in the infections of abdominal and genital sites could be life-saving, as in this report.},
year = {2013}
}
TY - JOUR T1 - A Case of Clostridium Perfringens Sepsis in the 29 Week Pregnant Woman with Diagnosed Fetal Omphalosel AU - Nezahat Gurler AU - Lutfiye Oksuz AU - Bahar Yuksel AU - Recep Has Y1 - 2013/05/30 PY - 2013 N1 - https://doi.org/10.11648/j.cmr.20130203.12 DO - 10.11648/j.cmr.20130203.12 T2 - Clinical Medicine Research JF - Clinical Medicine Research JO - Clinical Medicine Research SP - 29 EP - 31 PB - Science Publishing Group SN - 2326-9057 UR - https://doi.org/10.11648/j.cmr.20130203.12 AB - Although not common, postpartum and post-abortion infections caused by clostridia can be severe. Clostridial uterine infections start as localized chorioamnionitis as a result of an infection from the fetus and/or placental tissues. The infection may spread to the uterine wall and endometrial tissues, and, in the most severe cases, uterine necrosis accompanied by sepsis ensues. In this paper we report the presence of Clostridium perfringens isolated from blood culture and placental specimen after the termination of a 29 gestational week pregnancy. The woman had a history of having omphaloceled fetus and premature membrane rupture. Fetal omphalocele is a congenital defect of the abdominal wall that allows some of the abdominal organs to protrude through it. In order to find the focus of infection, blood and plasental specimen of the patient were examined. Blood cultures of the patient were evaluated by the BACTEC 9120 system. The identification of the bacteria was performed conventionally and confirmed by the automatized API 20A system. Antibiotic susceptibility testing was performed by E-test according to the recommendations of Clinical Laboratory and Standards Institute (CLSI). Although Clostridium spp is rarely isolated from blood cultures, anaerobically evaluation of blood cultures in the infections of abdominal and genital sites could be life-saving, as in this report. VL - 2 IS - 3 ER -
Email: