The aim of present study was to evaluate the effect of myrtenal, a monoterpene on plasma and tissues glycoprotein components in streptozotocin-induced diabetic rats. Diabetes was induced in overnight fasted experimental rats by a single intraperitoneal injection of streptozotocin (STZ; 40 mg/kg body weight) dissolved in 0.1 M citrate buffer at pH 4.5. STZ-injected animals were given 20 % glucose solution for 24 h to prevent initial drug-induced hypoglycemia mortality. The levels of plasma glucose, plasma and tissues glycoproteins such as hexose, hexosamine, fucose and sialic acid were significantly increased whereas plasma insulin levels were significantly decreased in diabetic rats. On oral administration myrtenal (80 mg/kg b.w.) once daily to diabetic rats for the period of 28 days brought back the levels of plasma and tissues glycoprotein components. Based on the present study, we propose that myrtenal possesses significant protective effect on glycoprotein metabolism.
| Published in |
Journal of Diseases and Medicinal Plants (Volume 2, Issue 1-1)
This article belongs to the Special Issue Pharmacological Action of Medicinal Plants: Health and Diseases |
| DOI | 10.11648/j.jdmp.s.2016020101.12 |
| Page(s) | 11-16 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2016. Published by Science Publishing Group |
Myrtenal, Glycoproteins, Wistar Rat, Streptozotocin, Hyperglycemia
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APA Style
Leelavinothan Pari, Ayyasamy Rathinam. (2016). Anti-diabetic Effect of Myrtenal on Plasma and Tissue Glycoproteins Components in STZ Induced Experimental Diabetic Rats. Journal of Diseases and Medicinal Plants, 2(1-1), 11-16. https://doi.org/10.11648/j.jdmp.s.2016020101.12
ACS Style
Leelavinothan Pari; Ayyasamy Rathinam. Anti-diabetic Effect of Myrtenal on Plasma and Tissue Glycoproteins Components in STZ Induced Experimental Diabetic Rats. J. Dis. Med. Plants 2016, 2(1-1), 11-16. doi: 10.11648/j.jdmp.s.2016020101.12
AMA Style
Leelavinothan Pari, Ayyasamy Rathinam. Anti-diabetic Effect of Myrtenal on Plasma and Tissue Glycoproteins Components in STZ Induced Experimental Diabetic Rats. J Dis Med Plants. 2016;2(1-1):11-16. doi: 10.11648/j.jdmp.s.2016020101.12
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Download@article{10.11648/j.jdmp.s.2016020101.12,
author = {Leelavinothan Pari and Ayyasamy Rathinam},
title = {Anti-diabetic Effect of Myrtenal on Plasma and Tissue Glycoproteins Components in STZ Induced Experimental Diabetic Rats},
journal = {Journal of Diseases and Medicinal Plants},
volume = {2},
number = {1-1},
pages = {11-16},
doi = {10.11648/j.jdmp.s.2016020101.12},
url = {https://doi.org/10.11648/j.jdmp.s.2016020101.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.s.2016020101.12},
abstract = {The aim of present study was to evaluate the effect of myrtenal, a monoterpene on plasma and tissues glycoprotein components in streptozotocin-induced diabetic rats. Diabetes was induced in overnight fasted experimental rats by a single intraperitoneal injection of streptozotocin (STZ; 40 mg/kg body weight) dissolved in 0.1 M citrate buffer at pH 4.5. STZ-injected animals were given 20 % glucose solution for 24 h to prevent initial drug-induced hypoglycemia mortality. The levels of plasma glucose, plasma and tissues glycoproteins such as hexose, hexosamine, fucose and sialic acid were significantly increased whereas plasma insulin levels were significantly decreased in diabetic rats. On oral administration myrtenal (80 mg/kg b.w.) once daily to diabetic rats for the period of 28 days brought back the levels of plasma and tissues glycoprotein components. Based on the present study, we propose that myrtenal possesses significant protective effect on glycoprotein metabolism.},
year = {2016}
}
TY - JOUR T1 - Anti-diabetic Effect of Myrtenal on Plasma and Tissue Glycoproteins Components in STZ Induced Experimental Diabetic Rats AU - Leelavinothan Pari AU - Ayyasamy Rathinam Y1 - 2016/02/23 PY - 2016 N1 - https://doi.org/10.11648/j.jdmp.s.2016020101.12 DO - 10.11648/j.jdmp.s.2016020101.12 T2 - Journal of Diseases and Medicinal Plants JF - Journal of Diseases and Medicinal Plants JO - Journal of Diseases and Medicinal Plants SP - 11 EP - 16 PB - Science Publishing Group SN - 2469-8210 UR - https://doi.org/10.11648/j.jdmp.s.2016020101.12 AB - The aim of present study was to evaluate the effect of myrtenal, a monoterpene on plasma and tissues glycoprotein components in streptozotocin-induced diabetic rats. Diabetes was induced in overnight fasted experimental rats by a single intraperitoneal injection of streptozotocin (STZ; 40 mg/kg body weight) dissolved in 0.1 M citrate buffer at pH 4.5. STZ-injected animals were given 20 % glucose solution for 24 h to prevent initial drug-induced hypoglycemia mortality. The levels of plasma glucose, plasma and tissues glycoproteins such as hexose, hexosamine, fucose and sialic acid were significantly increased whereas plasma insulin levels were significantly decreased in diabetic rats. On oral administration myrtenal (80 mg/kg b.w.) once daily to diabetic rats for the period of 28 days brought back the levels of plasma and tissues glycoprotein components. Based on the present study, we propose that myrtenal possesses significant protective effect on glycoprotein metabolism. VL - 2 IS - 1-1 ER -
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